Single-molecule and in silico dissection of the interaction between Polycomb repressive complex 2 and chromatin

Polycomb repressive complex 2 (PRC2) installs and spreads repressive histone methylation marks on eukaryotic chromosomes. Because of the key roles that PRC2 plays in development and disease, how this epigenetic machinery interacts with DNA and nucleosomes is of major interest. Nonetheless, the mecha...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Leicher, Rachel, Ge, Eva J., Lin, Xingcheng, Reynolds, Matthew J., Xie, Wenjun, Walz, Thomas, Zhang, Bin, Muir, Tom W., Liu, Shixin
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720148/
https://ncbi.nlm.nih.gov/pubmed/33208532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2003395117
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