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Single-molecule and in silico dissection of the interaction between Polycomb repressive complex 2 and chromatin
Polycomb repressive complex 2 (PRC2) installs and spreads repressive histone methylation marks on eukaryotic chromosomes. Because of the key roles that PRC2 plays in development and disease, how this epigenetic machinery interacts with DNA and nucleosomes is of major interest. Nonetheless, the mecha...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7720148/ https://ncbi.nlm.nih.gov/pubmed/33208532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2003395117 |
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