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Get rid of pancreatic cancer by inhibiting garbage disposal?: Comment on “UAE1 Inhibition mediates the unfolded protein response, DNA damage and caspase-dependent cell death in pancreatic cancer” by Rehemtulla et al

• stress pathways including the ER stress, the proteasome and the unfolded protein response (UPR) are increasingly reported to be suitable targets in PDAC; • UAE1 is the most abundant of two ubiquitin activating enzymes (UAE) regulating the initial step of the ER stress associated protein degradatio...

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Podrobná bibliografie
Vydáno v:Transl Oncol
Hlavní autoři: Geismann, Claudia, Arlt, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720072/
https://ncbi.nlm.nih.gov/pubmed/33285366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100968
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