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Get rid of pancreatic cancer by inhibiting garbage disposal?: Comment on “UAE1 Inhibition mediates the unfolded protein response, DNA damage and caspase-dependent cell death in pancreatic cancer” by Rehemtulla et al
• stress pathways including the ER stress, the proteasome and the unfolded protein response (UPR) are increasingly reported to be suitable targets in PDAC; • UAE1 is the most abundant of two ubiquitin activating enzymes (UAE) regulating the initial step of the ER stress associated protein degradatio...
Gardado en:
| Publicado en: | Transl Oncol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Neoplasia Press
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7720072/ https://ncbi.nlm.nih.gov/pubmed/33285366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100968 |
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