Paxilline Prevents the Onset of Myotonic Stiffness in Pharmacologically Induced Myotonia: A Preclinical Investigation

Reduced Cl(−) conductance causes inhibited muscle relaxation after forceful voluntary contraction due to muscle membrane hyperexcitability. This represents the pathomechanism of myotonia congenita. Due to the prevailing data suggesting that an increased potassium level is a main contributor, we stud...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Physiol
Egile Nagusiak: Hoppe, Kerstin, Sartorius, Tina, Chaiklieng, Sunisa, Wietzorrek, Georg, Ruth, Peter, Jurkat-Rott, Karin, Wearing, Scott, Lehmann-Horn, Frank, Klingler, Werner
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2020
Gaiak:
Physiology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719791/
https://ncbi.nlm.nih.gov/pubmed/33329012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.533946
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