Methadone Suppresses Neuronal Function and Maturation in Human Cortical Organoids

Accumulating evidence has suggested that prenatal exposure to methadone causes multiple adverse effects on human brain development. Methadone not only suppresses fetal neurobehavior and alters neural maturation, but also leads to long-term neurological impairment. Due to logistical and ethical issue...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Wu, Wei, Yao, Hang, Dwivedi, Ila, Negraes, Priscilla D., Zhao, Helen W., Wang, Juan, Trujillo, Cleber A., Muotri, Alysson R., Haddad, Gabriel G.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719724/
https://ncbi.nlm.nih.gov/pubmed/33328864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.593248
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