Complex oscillatory waves emerging from cortical organoids model early human brain network development

Structural and transcriptional changes during early brain maturation follow fixed developmental programs defined by genetics. However, whether this is true for functional network activity remains unknown, primarily due to experimental inaccessibility of the initial stages of the living human brain....

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Publié dans:Cell Stem Cell
Auteurs principaux: Trujillo, Cleber A., Gao, Richard, Negraes, Priscilla D., Gu, Jing, Buchanan, Justin, Preissl, Sebastian, Wang, Allen, Wu, Wei, Haddad, Gabriel G., Chaim, Isaac A., Domissy, Alain, Vandenberghe, Matthieu, Devor, Anna, Yeo, Gene W., Voytek, Bradley, Muotri, Alysson R.
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778040/
https://ncbi.nlm.nih.gov/pubmed/31474560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2019.08.002
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