IL-Y Aggravates Murine Chronic Graft-Versus-Host Disease by Enhancing T and B Cell Responses

IL-Y, a synthetic member of IL-12 cytokine family, was found to exert potent immunosuppressive effects by inhibiting the differentiation and activation of Th1 and Th17 cells. However, the role of IL-Y in the development of chronic graft-versus-host disease (cGVHD) remains unknown. Here, using murine...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Wan, Li, Jin, Ziqi, Hu, Bo, Lv, Kangkang, Lei, Lei, Liu, Yonghao, Song, Yuan, Zhu, Ying, Gong, Huanle, Xu, Mimi, Du, Yuanyuan, Xu, Yang, Liu, Haiyan, Wu, Depei, Liu, Yuejun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719702/
https://ncbi.nlm.nih.gov/pubmed/33329519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.559740
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