Inhibition of Acute Graft-versus-Host Disease with Retention of Graft-versus-Tumor Effects by Dimethyl Fumarate

Acute graft-versus-host disease (aGVHD) remains a clinical challenge and a major source of morbidity and mortality following allogeneic hematopoietic stem cell transplantation (allo-HSCT). Dimethyl fumarate (DMF), an activator of Nrf2, has been shown to have anti-inflammatory and immunomodulatory pr...

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Опубликовано в: :Front Immunol
Главные авторы: Han, Jingjing, Ma, Shoubao, Gong, Huanle, Liu, Shuangzhu, Lei, Lei, Hu, Bo, Xu, Yang, Liu, Haiyan, Wu, Depei
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2017
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702003/
https://ncbi.nlm.nih.gov/pubmed/29209333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01605
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