A carregar...
Drug-like properties in macrocycles above MW 1000: Backbone rigidity vs. side-chain lipophilicity
Large, macrocyclic peptides can achieve surprisingly high membrane permeability, although the properties that govern permeability in this chemical space are only beginning to come into focus. We generated two libraries of cyclic decapeptides with stable, cross-β conformations, and found that peptoid...
Na minha lista:
| Publicado no: | Angew Chem Int Ed Engl |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7719619/ https://ncbi.nlm.nih.gov/pubmed/32789999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202004550 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|