Population Pharmacokinetics of Metoclopramide in Infants, Children, and Adolescents

Metoclopramide is commonly used for gastroesophageal reflux. The aims of the present study were to develop a pediatric population pharmacokinetic (PopPK) model, which was applied to simulate the metoclopramide exposure following dosing used in clinical practice. Opportunistic pharmacokinetic data we...

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Pubblicato in:Clin Transl Sci
Autori principali: Ge, Shufan, Mendley, Susan R., Gerhart, Jacqueline G., Melloni, Chiara, Hornik, Christoph P., Sullivan, Janice E., Atz, Andrew, Delmore, Paula, Tremoulet, Adriana, Harper, Barrie, Payne, Elizabeth, Lin, Susan, Erinjeri, Jinson, Cohen‐Wolkowiez, Michael, Gonzalez, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719387/
https://ncbi.nlm.nih.gov/pubmed/32324313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12803
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