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Pharmacokinetics, Pharmacodynamics, and Exposure‐Response of Lanadelumab for Hereditary Angioedema

Hereditary angioedema (HAE) with C1 inhibitor deficiency is a rare disorder characterized by unpredictable, potentially life‐threatening recurrent angioedema attacks. Lanadelumab is a fully human monoclonal antibody with selective binding to active plasma kallikrein, and prevents the formation of cl...

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Publicado en:Clin Transl Sci
Autores principales: Wang, Yi, Marier, Jean-Francois, Kassir, Nastya, Chang, Colin, Martin, Patrick
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719386/
https://ncbi.nlm.nih.gov/pubmed/32407574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12806
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