hIL‐7‐hyFc, A Long‐Acting IL‐7, Increased Absolute Lymphocyte Count in Healthy Subjects

A low lymphocyte count puts immune‐compromised patients at risk of mortality. hIL‐7‐hyFc is a homodimeric interleukin‐7 (IL‐7), a potent T‐cell amplifier, fused to the hybridizing IgD/IgG4 immunoglobulin domain. We performed a randomized, double‐blind, placebo‐controlled, dose‐escalation, phase I st...

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Enregistré dans:
Détails bibliographiques
Publié dans:Clin Transl Sci
Auteurs principaux: Lee, Sang Won, Choi, Donghoon, Heo, MinKyu, Shin, Eui‐Cheol, Park, Su‐Hyung, Kim, So Jeong, Oh, Yeon‐Kyung, Lee, Byung Ha, Yang, Se Hwan, Sung, Young Chul, Lee, Howard
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719369/
https://ncbi.nlm.nih.gov/pubmed/32339447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12800
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