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Heat shock protein 90α increases superoxide generation from neuronal nitric oxide synthases

Neuronal nitric oxide synthase (nNOS) generates superoxide, particularly at sub-optimal l-arginine (L-Arg) substrate concentrations. Heat shock protein 90 (Hsp90) was reported to inhibit superoxide generation from nNOS protein. However, commercially available Hsp90 product from bovine brain tissues...

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Detalhes bibliográficos
Publicado no:J Inorg Biochem
Main Authors: Zheng, Huayu, Weaver, John M., Feng, Changjian
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719093/
https://ncbi.nlm.nih.gov/pubmed/33181440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2020.111298
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