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CaMKII binding to GluN2B at S1303 Has No Role in Acute or Inflammatory Pain

Activation of Ca(2+)/calmodulin kinase II (CaMKII) and the N-Methyl D-aspartate receptor (NMDAR), particularly its GluN2B subunit, contribute to the central sensitization of nociceptive pathways and persistent pain. Using mutant mice wherein the activity-driven binding of CaMKII to S1303 in GluN2B i...

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Publicat a:Brain Res
Autors principals: Maduka, Uche P., White, Stephanie R., Joiner, Mei-Ling A., Hell, Johannes W., Hammond, Donna L
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719074/
https://ncbi.nlm.nih.gov/pubmed/33068634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2020.147154
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