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Mannose-Modified Liposome Co-Delivery of Human Papillomavirus Type 16 E7 Peptide and CpG Oligodeoxynucleotide Adjuvant Enhances Antitumor Activity Against Established Large TC-1 Grafted Tumors in Mice

BACKGROUND: Previously, we demonstrated the therapeutic efficacy of a human papillomavirus (HPV) vaccine, including HPV16 E7 peptide and CpG oligodeoxynucleotides (CpG ODN), against small TC-1 grafted tumors. Here, we developed an HPV16 E7 peptide and CpG ODN vaccine delivered using liposomes modifi...

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Detalles Bibliográficos
Publicado en:Int J Nanomedicine
Main Authors: Zhao, Yan, Wang, Huan, Yang, Yang, Jia, Wendan, Su, Tong, Che, Yuxin, Feng, Yixin, Yuan, Xuemei, Wang, Xuelian
Formato: Artigo
Idioma:Inglês
Publicado: Dove 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7718974/
https://ncbi.nlm.nih.gov/pubmed/33293808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S275670
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