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Nonlinear mechanics of lamin filaments and the meshwork topology build an emergent nuclear lamina

The nuclear lamina—a meshwork of intermediate filaments termed lamins—is primarily responsible for the mechanical stability of the nucleus in multicellular organisms. However, structural-mechanical characterization of lamin filaments assembled in situ remains elusive. Here, we apply an integrative a...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Sapra, K. Tanuj, Qin, Zhao, Dubrovsky-Gaupp, Anna, Aebi, Ueli, Müller, Daniel J., Buehler, Markus J., Medalia, Ohad
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7718915/
https://ncbi.nlm.nih.gov/pubmed/33277502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20049-8
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