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Chemical-Genetic Interactions with the Proline Analog L-Azetidine-2-Carboxylic Acid in Saccharomyces cerevisiae

Non-proteinogenic amino acids, such as the proline analog L-azetidine-2-carboxylic acid (AZC), are detrimental to cells because they are mis-incorporated into proteins and lead to proteotoxic stress. Our goal was to identify genes that show chemical-genetic interactions with AZC in Saccharomyces cer...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Berg, Matthew D., Zhu, Yanrui, Isaacson, Joshua, Genereaux, Julie, Loll-Krippleber, Raphaël, Brown, Grant W., Brandl, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7718759/
https://ncbi.nlm.nih.gov/pubmed/33082270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.120.401876
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