Metformin Prevents Follicular Atresia in Aging Laying Chickens through Activation of PI3K/AKT and Calcium Signaling Pathways

Increased follicular atresia occurs with aging and results in reduced fecundity in laying chickens. Therefore, relieving follicular atresia of aging poultry is a crucial measure to maintain sustained high laying performance. As an antiaging agent, metformin was reported to play important roles in pr...

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Publicat a:Oxid Med Cell Longev
Autors principals: Yao, Jinwei, Ma, Yanfen, Zhou, Shuo, Bao, Tingting, Mi, Yuling, Zeng, Weidong, Li, Jian, Zhang, Caiqiao
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7718058/
https://ncbi.nlm.nih.gov/pubmed/33294120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/3648040
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