AXL Inhibition Enhances MEK Inhibitor Sensitivity in Malignant Peripheral Nerve Sheath Tumors

Dysregulation of the receptor tyrosine kinase AXL is known to promote cancer cell growth and survival in many sarcomas, including the rare subtype, malignant peripheral nerve sheath tumors (MPNST). MPNSTs are largely chemoresistant and carry a poor prognosis. AXL is an attractive potential therapeut...

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Detaylı Bibliyografya
Yayımlandı:J Cancer Sci Clin Ther
Asıl Yazarlar: Landers, Sharon M., Bhalla, Angela D., Ma, XiaoYan, Lusby, Kristelle, Ingram, Davis, Al Sannaa, Ghadah, Wang, Wei-Lien, Lazar, Alexander J., Torres, Keila E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7717506/
https://ncbi.nlm.nih.gov/pubmed/33283192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26502/jcsct.5079091
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