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Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor

The prognosis of recurrent malignant peripheral nerve sheath tumors (MPNST) is dismal, with surgical resection being the only definitive salvage therapy. Treatment with chemoradiation approaches has not significantly improved patient outcomes. Similarly, trials of therapies targeting MPNST genomic d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:NPJ Precis Oncol
Hauptverfasser: Nagabushan, Sumanth, Lau, Loretta M. S., Barahona, Paulette, Wong, Marie, Sherstyuk, Alexandra, Marshall, Glenn M., Tyrrell, Vanessa, Wegner, Eva A., Ekert, Paul G., Cowley, Mark J., Mayoh, Chelsea, Trahair, Toby N., Crowe, Philip, Anazodo, Antoinette, Ziegler, David S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7881142/
https://ncbi.nlm.nih.gov/pubmed/33580196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-021-00145-8
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