Somatic mutations and T-cell clonality in patients with immunodeficiency

Common variable immunodeficiency (CVID) and other late-onset immunodeficiencies often co-manifest with autoimmunity and lymphoproliferation. The pathogenesis of most cases is elusive, as only a minor subset harbors known monogenic germline causes. The involvement of both B and T cells is, however, i...

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Опубликовано в: :Haematologica
Главные авторы: Savola, Paula, Martelius, Timi, Kankainen, Matti, Huuhtanen, Jani, Lundgren, Sofie, Koski, Yrjö, Eldfors, Samuli, Kelkka, Tiina, Keränen, Mikko A.I., Ellonen, Pekka, Kovanen, Panu E., Kytölä, Soili, Saarela, Janna, Lähdesmäki, Harri, Seppänen, Mikko R.J., Mustjoki, Satu
Формат: Artigo
Язык:Inglês
Опубликовано: Fondazione Ferrata Storti 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7716374/
https://ncbi.nlm.nih.gov/pubmed/33256375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.220889
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