TBIO-15. MODELING DEVELOPMENTAL GENE EXPRESSION DYNAMICS AT CELLULAR RESOLUTION TO INTERPRET PEDIATRIC BRAIN TUMOR TRANSCRIPTIONAL PROGRAMS

A central challenge in understanding the biology of pediatric brain tumors is defining the cellular and molecular context where oncogenesis occurs. We hypothesize that spatiotemporally restricted cell types are uniquely susceptible to specific genetic alterations, which alter normal neurodevelopment...

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Bibliografiska uppgifter
I publikationen:Neuro Oncol
Huvudupphovsmän: Jessa, Selin, Kabir, Nisha, Vladoiu, Maria, Hébert, Steven, Taylor, Michael D, Jabado, Nada, Kleinman, Claudia L
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2020
Ämnen:
Tumor Biology (not fitting a specific disease category)
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715983/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.842
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