TBIO-27. RASOPATHIES AND BRAIN TUMOROGENESIS: ARE SOS1 MUTATIONS ARE CONCERNED?

Germ line gain-of-function mutations in several members of the RAS/MAPK pathway, including PTPN11 are associated with signalopathies named Rasopathies and known as Noonan syndrome and closely related conditions. Patients harboring Rasopathies are at increased risk of myeloproliferative diseases and...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Abdelmoula, Nouha Bouayed, Louati, Rim, Abdelmoula, Balkiss, Aloulou, Samir
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Tumor Biology (not fitting a specific disease category)
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715893/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.850
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