EPEN-18. CROSS-SPECIES GENOMICS IDENTIFIES GLI2 AS AN ONCOGENE OF C11orf95 FUSION-POSITIVE SUPRATENTORIAL EPENDYMOMA

The majority of supratentorial ependymomas (ST-EPN) are driven by fusions between RELA and a zinc finger containing gene, C11orf95. Apart from fusions to the Hippo effector YAP1, which affects a small group of infant patients, the oncogenic mechanism of remaining ST-EPNs is unclear. Aiming at refini...

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Опубликовано в: :Neuro Oncol
Главные авторы: Zheng, Tuyu, Ghasemi, David R, Okonechnikov, Konstantin, Korshunov, Andrey, Sill, Martin, Hübner, Jens-Martin, Maaß, Kendra K, Snuderl, Matija, Gojo, Johannes, Schüller, Ulrich, Gerber, Nicolas U, Hernáiz-Driever, Pablo, Milde, Till, Sturm, Dominik, Chapman, Rebecca, Grundy, Richard G, von Deimling, Andreas, Jones, David T W, Kool, Marcel, Pfister, Stefan M, Sahm, Felix, Kawauchi, Daisuke, Pajtler, Kristian W
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2020
Предметы:
Ependymoma
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715864/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.156
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