LGG-30. TRAMETINIB-ASSOCIATED HYPONATREMIA IN A CHILD WITH LOW GRADE GLIOMA IS NOT SEEN FOLLOWING TREATMENT WITH ALTERNATIVE MEK INHIBITOR

Molecularly targeted therapy with MEK inhibitors is increasingly being incorporated into the treatment of pediatric low-grade gliomas (LGGs). Trametinib is an orally available MEK1/2 inhibitor that has demonstrated tumor control in LGGs with BRAF alterations. Safe expansion of MEK inhibitor therapy...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Lazow, Margot A, Lawson, Sarah A, Salloum, Ralph, Hummel, Trent R, Smiley, Natasha Pillay, DeWire-Schottmiller, Mariko D, Fouladi, Maryam, de Blank, Peter M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Low Grade Glioma
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715810/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.412
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