RARE-07. THE LANDSCAPE OF GENOMIC ALTERATIONS IN ADAMANTINOMATOUS CRANIOPHARYNGIOMAS

INTRODUCTION: Adamantinomatous craniopharyngiomas (ACPs) are characterized by activating mutations in the CTNNB1 gene. Here we perform a comprehensive genomic analysis of 23 ACPs to define the landscape of genomic alterations in this disease. METHODS: We performed whole-genome sequencing of 24 ACPs...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Khadka, Prasidda, Prince, Eric, Lu, Sophie, Santagata, Sandro, Ligon, Keith, Manley, Peter, Beroukhim, Rameen, Hankinson, Todd, Bandopadhayay, Pratiti
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Craniopharyngioma and Rare Tumors
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715698/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.718
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