RARE-08. CYST FLUID CYTOKINES MAY PROMOTE EPITHELIAL-TO-MESENCHYMAL TRANSITION IN PEDIATRIC ADAMANTINOMATOUS CRANIOPHARYNGIOMA

BACKGROUND: Despite poor clinical outcomes, no targeted therapies have been established for the treatment of Adamantinomatous Craniopharyngioma (ACP). The only known genetic aberration is a mutation in CTNNB1 that results in the nuclear accumulation of beta-catenin. Nuclear beta-catenin is an establ...

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Udgivet i:Neuro Oncol
Main Authors: Vijmasi, Trinka, Prince, Eric, Hengartner, Astrid, Agwu, Chibueze, Staulcup, Susan, Pavlova, Maryna, Griesinger, Andrea, Donson, Andrew, Dorris, Kathleen, Handler, Michael, Hankinson, Todd
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Craniopharyngioma and Rare Tumors
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715255/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.719
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