LGG-27. TARGETED THERAPY FOR PEDIATRIC LOW-GRADE GLIOMAS AND PLEXIFORM NEUROFIBROMAS WITH TRAMETINIB

BACKGROUND: Targeted therapy aimed at modulating the RAS/RAF/MEK/ERK pathway is of increasing interest for patients with plexiform neurofibromas and low-grade gliomas. Trametinib is an FDA-approved MEK inhibitor that has little published pediatric experience to date. METHODS: A retrospective chart r...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Nguyen, Tiffany, McMahon, Kathleen, Hemenway, Molly, Levy, Jean Mulcahy, Foreman, Nicholas, Dorris, Kathleen
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Low Grade Glioma
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715454/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.409
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