LGG-04. A PHASE II RE-TREATMENT STUDY OF SELUMETINIB FOR RECURRENT OR PROGRESSIVE PEDIATRIC LOW-GRADE GLIOMA (pLGG): A PEDIATRIC BRAIN TUMOR CONSORTIUM (PBTC) STUDY

The PBTC conducted a re-treatment study (NCT01089101) evaluating selumetinib (AZD6244, ARRY-142886), a MEK I/II inhibitor, in children with recurrent/progressive pLGG. Eligible patients must have previously enrolled on PBTC-029 or PBTC-029B and progressed after coming off treatment with selumetinib....

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Bibliografische gegevens
Gepubliceerd in:Neuro Oncol
Hoofdauteurs: Fangusaro, Jason, Onar-Thomas, Arzu, Wu, Shengjie, Poussaint, Tina Young, Packer, Roger, Kilburn, Lindsay, Qaddoumi, Ibrahim, Dhall, Girish, Pollack, Ian F, Lenzen, Alicia, Partap, Sonia, Fouladi, Maryam, Dunkel, Ira
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
Onderwerpen:
Low Grade Glioma
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715425/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.389
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