MBRS-71. ATAXIA TELANGIECTASIA AND RAD3-RELATED PROTEIN ATTENUATES DNA DAMAGE AND IS A THERAPEUTIC TARGET IN Myc-DRIVEN MEDULLOBLASTOMA

Group 3 medulloblastoma tumors (Myc-MB), and particularly the 3γ subtype, have the worst prognosis and show a 5-year overall survival of less than 40%. Group 3 tumors are often accompanied by Myc amplification and have a higher rate of metastatic disease and relapse. Unfortunately, therapeutic strat...

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Enregistré dans:
Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Abdel-Hafiz, Ahmed, Madhavan, Krishna, Balakrishnan, Ilango, Pierce, Angela, Wang, Dong, Danis, Etienne, Serkova, Natalie, Venkataraman, Sujatha, Vibhakar, Rajeev
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Medulloblastoma (Research)
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715361/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.575
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