TBIO-14. CHARACTERISATION OF THE ARGININE PATHWAY ENZYMES IN PAEDIATRIC BRAIN TUMOURS TO DETERMINE SUSCEPTIBILITY TO THERAPEUTIC ARGININE DEPLETION

INTRODUCTION: Extracellular arginine dependency (auxotrophy) is increasingly being recognised in several tumours. This is due to the inability of cancer cells to recycle or synthesise intracellular arginine through the urea cycle pathway compared to normal cells. Whilst adult glioblastoma is known t...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neuro Oncol
Egile Nagusiak: Bishop, Eleanor, Dimitrova, Monika, Storer, Lisa, Grundy, Richard, Dandapani, Madhumita
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2020
Gaiak:
Tumor Biology (not fitting a specific disease category)
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715343/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.841
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