ETMR-19. SINGLE CELL ANALYSES OF ETMRs REVEAL THAT C19MC+ POPULATION DRIVES CELL CYCLE PROGRESSION AND STEM CELL MAINTENANCE

Embryonal tumors with multilayered rosettes (ETMRs) are highly fatal diseases characterized by recurrent amplification of C19MC, an oncogenic miRNA cluster. While C19MC was discovered as a major driver of ETMRs, its direct role in ETMRs remains unknown. As ETMRs exhibit significant heterogeneity in...

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Vydáno v:Neuro Oncol
Hlavní autoři: Mumal, Iqra, Xu, Liming, Yao, Fupan, Suwal, Tannu, Fan, Xiaolian, Lu, Mei, Huang, Annie
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
ETMR and other Embryonal Tumors
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715313/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.222
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