IMMU-15. PROTEOGENOMIC DISCOVERY OF NOVEL TUMOR PEPTIDES AS NEOANTIGENS FOR PERSONALIZED T CELL IMMUNOTHERAPY IN MEDULLOBLASTOMA

T cell immunotherapies are promising new tools to combat high-risk subgroups of medulloblastoma without increasing the late effects burden. The ideal target antigen of an effective antitumor T-cell response is abundantly expressed by tumor cells but not by normal tissues, in order to limit off-targe...

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Опубликовано в: :Neuro Oncol
Главные авторы: Rivero-Hinojosa, Samuel, Grant, Melanie, Panigrahi, Aswini, Zhang, Huizhen, Caisova, Veronika, Bollard, Catherine, Rood, Brian
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2020
Предметы:
Immunotherapy
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715278/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.371
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