Interleukin (IL)-12 and IL-18 Synergize to Promote MAIT Cell IL-17A and IL-17F Production Independently of IL-23 Signaling

IL-23 is considered a critical regulator of IL-17 in Th17 cells; however, its requirement for inducing IL-17 production in other human immune subsets remains incompletely understood. Mucosal associated invariant T (MAIT) cells uniformly express retinoic acid receptor-related orphan receptor gamma t...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Cole, Suzanne, Murray, Janine, Simpson, Catherine, Okoye, Remi, Tyson, Kerry, Griffiths, Meryn, Baeten, Dominique, Shaw, Stevan, Maroof, Asher
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7714946/
https://ncbi.nlm.nih.gov/pubmed/33329560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.585134
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