NK cells in pancreatic cancer demonstrate impaired cytotoxicity and a regulatory IL-10 phenotype

Pancreatic ductal adenocarcinoma (PDAC) is one of the most common tumor subtypes and remains associated with very poor survival. T cell infiltration into tumor tissue is associated with improved clinical outcome but little is known regarding the potential role of NK cells in disease control. Here we...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Marcon, Francesca, Zuo, Jianmin, Pearce, Hayden, Nicol, Samantha, Margielewska-Davies, Sandra, Farhat, Mustafa, Mahon, Brinder, Middleton, Gary, Brown, Rachel, Roberts, Keith J., Moss, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7714501/
https://ncbi.nlm.nih.gov/pubmed/33299656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1845424
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