β-d-2′-C-Methyl-2,6-diaminopurine Ribonucleoside Phosphoramidates are Potent and Selective Inhibitors of Hepatitis C Virus (HCV) and Are Bioconverted Intracellularly to Bioactive 2,6-Diaminopurine and Guanosine 5′-Triphosphate Forms

Lignende værker

• Intracellular metabolism and potential cardiotoxicity of a β-D-2’-C-methyl-2,6-diaminopurine ribonucleoside phosphoramidate that inhibits hepatitis C virus replication
  af: Tao, Sijia, et al.
  Udgivet: (2019)
• Biochemical Characterization of the Active Anti-Hepatitis C Virus Metabolites of 2,6-Diaminopurine Ribonucleoside Prodrug Compared to Sofosbuvir and BMS-986094
  af: Ehteshami, Maryam, et al.
  Udgivet: (2016)
• Synthesis and Evaluation of 2,6-Modified Purine 2′-C-Methyl Ribonucleosides as Inhibitors of HCV Replication
  af: Zhou, Longhu, et al.
  Udgivet: (2015)
• Scaleable processes for the synthesis of (−)-β-D-2,6-diaminopurine dioxolane (Amdoxovir, DAPD) and (−)-β-D-2-aminopurine dioxolane (APD)
  af: Zhou, Longhu, et al.
  Udgivet: (2012)
• Mutant of Yeast Sensitive to 2,6-Diaminopurine
  af: Lomax, Christopher A., et al.
  Udgivet: (1969)