LncRNA TSLNC8 synergizes with EGFR inhibitor osimertinib to inhibit lung cancer tumorigenesis by blocking the EGFR-STAT3 pathway

The roles of lncRNA TSLNC8 and its synergetic effects with osimertinib remain unknown in lung cancer. qRT-PCR or western blotting was performed to determine the expression levels of TSLNC8, EGFR and STAT3. Colony formation and MTT assays were used to evaluate cell proliferation. Transwell and wound...

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Опубликовано в: :Cell Cycle
Главные авторы: Zhou, Su-Zhen, Li, Han, Wang, Zhi-Wan, Wang, Ming-Hang, Li, Ning, Wang, Yan-Fang
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2020
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7714453/
https://ncbi.nlm.nih.gov/pubmed/33064977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2020.1820697
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