MNAT1 promotes proliferation and the chemo-resistance of osteosarcoma cell to cisplatin through regulating PI3K/Akt/mTOR pathway

BACKGROUND: MNAT1 (menage a trois 1, MAT1), a cyclin-dependent kinase-activating kinase (CAK) complex, highly expressed in diverse cancers and was involved in cancer molecular pathogenesis. However, its deliverance profile and biological function in osteosarcoma (OS) remain unclear. METHODS: The exp...

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Publicat a:BMC Cancer
Autors principals: Qiu, Chensheng, Su, Weiliang, Shen, Nana, Qi, Xiaoying, Wu, Xiaolin, Wang, Kai, Li, Lin, Guo, Zhu, Tao, Hao, Wang, Guanrong, Chen, Bohua, Xiang, Hongfei
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7713032/
https://ncbi.nlm.nih.gov/pubmed/33272245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07687-3
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