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Enhancing the Solubility of Curcumin Using a Solid Dispersion System with Hydroxypropyl-β-Cyclodextrin Prepared by Grinding, Freeze-Drying, and Common Solvent Evaporation Methods

Cyclodextrins (CDs) and their derivatives significantly increase drug solubility by forming drug/CD complexes known as solid dispersions (SDs), which consist of an inclusion complex (IC), where the drug is entrapped within the CD cavity, and a non-IC. Here, the SDs of curcumin (CUR) and hydroxypropy...

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Detalhes bibliográficos
Publicado no:Pharmacy (Basel)
Main Authors: Mai, Nguyen Ngoc Sao, Nakai, Riko, Kawano, Yayoi, Hanawa, Takehisa
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712988/
https://ncbi.nlm.nih.gov/pubmed/33147710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmacy8040203
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