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The pleiotropic role of p53 in functional/dysfunctional neurons: focus on pathogenesis and diagnosis of Alzheimer’s disease

BACKGROUND: Understanding the earliest pathophysiological changes of Alzheimer’s disease (AD) may aid in the search for timely diagnostic biomarkers and effective disease-modifying therapies. The p53 protein is mostly known for its role in tumor suppression. However, emerging evidence supports that...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Abate, Giulia, Frisoni, Giovanni B., Bourdon, Jean-Christophe, Piccirella, Simona, Memo, Maurizio, Uberti, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712978/
https://ncbi.nlm.nih.gov/pubmed/33272326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-020-00732-0
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