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Post-translational Modifications of the p53 Protein and the Impact in Alzheimer’s Disease: A Review of the Literature

Our understanding of Alzheimer’s disease (AD) pathogenesis has developed with several hypotheses over the last 40 years, including the Amyloid and Tau hypotheses. More recently, the p53 protein, well-known as a genome guardian, has gained attention for its potential role in the early evolution of AD...

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Detalhes bibliográficos
Main Authors: James S. Clark, Rakez Kayed, Giulia Abate, Daniela Uberti, Paul Kinnon, Simona Piccirella
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-04-01
Colecção:Frontiers in Aging Neuroscience
Assuntos:
p53
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fnagi.2022.835288/full
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