NLRP3 inflammasome deficiency attenuates metabolic disturbances involving alterations in the gut microbial profile in mice exposed to high fat diet

Obesity-related diseases (e.g. type 2 diabetes mellitus and cardiovascular disorders) represent an increasing health problem worldwide. NLRP3 inflammasome activation may underlie obesity-induced inflammation and insulin resistance, and NLRP3 deficient mice exposed to high fat diet (HFD) appear to be...

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Pubblicato in:Sci Rep
Autori principali: Sokolova, Marina, Yang, Kuan, Hansen, Simen H., Louwe, Mieke C., Kummen, Martin, Hov, Johannes E. R., Sjaastad, Ivar, Berge, Rolf K., Halvorsen, Bente, Aukrust, Pål, Yndestad, Arne, Ranheim, Trine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712828/
https://ncbi.nlm.nih.gov/pubmed/33273482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76497-1
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