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A Recombinant Zika Virus Envelope Protein with Mutations in the Conserved Fusion Loop Leads to Reduced Antibody Cross-Reactivity upon Vaccination

Zika virus (ZIKV) is a zoonotic, human pathogenic, and mosquito-borne flavivirus. Its distribution is rapidly growing worldwide. Several attempts to develop vaccines for ZIKV are currently ongoing. Central to most vaccination approaches against flavivirus infections is the envelope (E) protein, whic...

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Publicat a:Vaccines (Basel)
Autors principals: Berneck, Beatrice Sarah, Rockstroh, Alexandra, Fertey, Jasmin, Grunwald, Thomas, Ulbert, Sebastian
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712286/
https://ncbi.nlm.nih.gov/pubmed/33066262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8040603
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