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A Recombinant Zika Virus Envelope Protein with Mutations in the Conserved Fusion Loop Leads to Reduced Antibody Cross-Reactivity upon Vaccination

Zika virus (ZIKV) is a zoonotic, human pathogenic, and mosquito-borne flavivirus. Its distribution is rapidly growing worldwide. Several attempts to develop vaccines for ZIKV are currently ongoing. Central to most vaccination approaches against flavivirus infections is the envelope (E) protein, whic...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Berneck, Beatrice Sarah, Rockstroh, Alexandra, Fertey, Jasmin, Grunwald, Thomas, Ulbert, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712286/
https://ncbi.nlm.nih.gov/pubmed/33066262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8040603
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