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A Recombinant Zika Virus Envelope Protein with Mutations in the Conserved Fusion Loop Leads to Reduced Antibody Cross-Reactivity upon Vaccination

Zika virus (ZIKV) is a zoonotic, human pathogenic, and mosquito-borne flavivirus. Its distribution is rapidly growing worldwide. Several attempts to develop vaccines for ZIKV are currently ongoing. Central to most vaccination approaches against flavivirus infections is the envelope (E) protein, whic...

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書目詳細資料
發表在:Vaccines (Basel)
Main Authors: Berneck, Beatrice Sarah, Rockstroh, Alexandra, Fertey, Jasmin, Grunwald, Thomas, Ulbert, Sebastian
格式: Artigo
語言:Inglês
出版: MDPI 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7712286/
https://ncbi.nlm.nih.gov/pubmed/33066262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8040603
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