A Novel Kindred with Familial Gastrointestinal Stromal Tumors Caused by a Rare KIT Germline Mutation (N655K): Clinico-Pathological Presentation and TKI Sensitivity

Gastrointestinal stromal tumors (GISTs), the most common mesenchymal tumors of the gastrointestinal tract, are characterized by activating mutations in KIT or PDGFRA genes. The vast majority of GISTs are sporadic, but rare hereditary forms have been reported, often featuring multifocality and younge...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Pers Med
Hlavní autoři: Fornasarig, Mara, Gasparotto, Daniela, Foltran, Luisa, Campigotto, Michele, Lombardi, Sara, Del Savio, Elisa, Buonadonna, Angela, Puglisi, Fabio, Sulfaro, Sandro, Canzonieri, Vincenzo, Cannizzaro, Renato, Maestro, Roberta
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
Case Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7711910/
https://ncbi.nlm.nih.gov/pubmed/33212994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm10040234
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky