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Structural and Biophysical Insights into the TCRαβ Complex in Chickens
In this work, chicken HPAIV H5N1 epitope-specific TCRαβ (ch-TCRαβ) was isolated and its structure was determined. The Cα domain of ch-TCRαβ does not exhibit the typical structure of human TCRαβ, and the DE loop extends outward, resulting in close proximity between the Cα domain of ch-TCRαβ and CD3εδ...
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| Publié dans: | iScience |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7711287/ https://ncbi.nlm.nih.gov/pubmed/33305184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101828 |
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