Podophyllotoxin Exposure Causes Spindle Defects and DNA Damage-Induced Apoptosis in Mouse Fertilized Oocytes and Early Embryos

Podophyllotoxin (PPT) is a kind of lignans extracted from the roots and stems of the genus Podophyllum from the tiller family, and it has been widely used in the treatment of condyloma acuminatum, multiple superficial epithelioma in the clinics. However, PPT has been reported to be toxic and can cau...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Cell Dev Biol
Prif Awduron: Hu, Lin-Lin, Liao, Bi-Yun, Wei, Jing-Xi, Ling, Yan-Lan, Wei, Yu-Xia, Liu, Zhong-Lin, Luo, Xiao-Qiong, Wang, Jun-Li
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020
Pynciau:
Cell and Developmental Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710938/
https://ncbi.nlm.nih.gov/pubmed/33330491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.600521
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