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Exposure to podophyllotoxin inhibits oocyte meiosis by disturbing meiotic spindle formation

Podophyllotoxin is used as medical cream which is widely applied to genital warts and molluscum contagiosum. Although previous study showed that podophyllotoxin had minimal toxicity, it was forbidden to use during pregnancy since it might be toxic to the embryos. In present study we used mouse as th...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Hu, Lin-Lin, Zhou, Xin, Zhang, Hao-Lin, Wu, Lan-Lan, Tang, Lian-Sheng, Chen, Ling-Li, Duan, Jin-Liang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033908/
https://ncbi.nlm.nih.gov/pubmed/29976965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28544-1
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