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Exposure to podophyllotoxin inhibits oocyte meiosis by disturbing meiotic spindle formation

Podophyllotoxin is used as medical cream which is widely applied to genital warts and molluscum contagiosum. Although previous study showed that podophyllotoxin had minimal toxicity, it was forbidden to use during pregnancy since it might be toxic to the embryos. In present study we used mouse as th...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Hu, Lin-Lin, Zhou, Xin, Zhang, Hao-Lin, Wu, Lan-Lan, Tang, Lian-Sheng, Chen, Ling-Li, Duan, Jin-Liang
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033908/
https://ncbi.nlm.nih.gov/pubmed/29976965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28544-1
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