Intracerebroventricular Administration of Interferon-Alpha Induced Depressive-Like Behaviors and Neurotransmitter Changes in Rhesus Monkeys

Interferon-alpha (IFN-α) is a cytokine widely used in the treatment of brain cancers and virus infections with side effects including causing depression. Monoamine neurotransmitter systems have been found playing important roles in peripheral IFN-α-induced depression, but how peripheral IFN-α access...

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Veröffentlicht in:Front Neurosci
Hauptverfasser: Li, Zhifei, Li, Zhaoxia, Lv, Xiaoman, Li, Zhaofu, Xiong, Lei, Hu, Xintian, Qin, Dongdong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710898/
https://ncbi.nlm.nih.gov/pubmed/33328856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.585604
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