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Bidirectional Causal Associations Between Inflammatory Bowel Disease and Ankylosing Spondylitis: A Two-Sample Mendelian Randomization Analysis

BACKGROUND: Associations between inflammatory bowel disease (IBD) [including ulcerative colitis (UC) and Crohn’s disease (CD)] and ankylosing spondylitis (AS) were discovered in observational studies, but no evidence supported the causal relationship between the two diseases. METHODS: We employed tw...

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發表在:Front Genet
Main Authors: Cui, Zhiyong, Hou, Guojin, Meng, Xiangyu, Feng, Hui, He, Baichuan, Tian, Yun
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710797/
https://ncbi.nlm.nih.gov/pubmed/33329731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.587876
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